6-溴雄烯酮 38632-00-7 6-溴雄烯酮 产品别名: 6-溴-3,17-二氧雄烷, 6-溴雄烯酮，6-溴雄烷， 产品含量: 97% 质量标准: 企业标准 产品含量: 97% 包装规格: 1kg 分子量: c19h26 br o2=366.41 理化性质:白色固体,见光,受热易分解变色,宜冷冻避光贮存.熔点:100-102℃. 制备方法:由4-雄烯二酮与溴素反应制备. 用途:本品是一种医药中间体. （6-溴雄烯酮） Product Name：6-Bromoandrostenedione CAS Number：38632-00-7 A selective inhibitor of aromatase (estrogen synthetase) would be a useful pharmacological tool with potential therapeutic application. We have found that 6 alpha-bromoandrostenedione (6 alpha-BrA) is a competitive inhibitor of human ntal aromatase with respect to androstenedione, with an apparent Ki of 3.4 nM, while 6 beta-BrA is a mechanism-based irreversible inhibitor with an apparent Ki of 0.8 microM and a kinact of 0.025 min-1. Aromatase activity was measured by tritium release into water from the 1 beta position of [1(-3)H,4(-14)C]androstenedione in reaction mixtures containing NADPH and the aromatase.
